We invest in frontier neuro.
We back founders building transformative technologies that read, repair, and enhance the brain, and AI that learns from it.

What we invest in:

  • NeuroAIBrain data, connectomics, and foundation models. AI that learns from the brain, and AI that helps understand it.
  • Neurotech & BCIImplants, wearables and neural interfaces that read and write to the brain and nervous system.
  • Precision NeuroShifting from population-wide care to approaches built on each patient's profile.
  • New ModalitiesRNA, gene, cell therapies, and delivery technologies that transcend conventional small molecules.
  • Human AugmentationTechnologies that improve cognition, focus, mood, and sleep, and keep the brain healthy.
  • Platforms & TherapeuticsHorizontal platforms, AI-driven discovery, and novel compounds.
  • Digital Health & TherapeuticsApps, wearables, and platforms that help patients treat, prevent, or manage disease.
  • NeurometabolismHow drugs, diet, exercise, and gut microbiota affect metabolism and health.
  • UnchartedBuilding something that doesn’t fit these categories? If it’s frontier, we want to hear from you.

Companies we back:

  • Aerska, RNAi medicines to treat, delay, and prevent neurodegeneration.
  • Ancilia, CRISPR for live biotherapeutics and bacterial products.
  • Beckley Psytech, short duration, rapid-acting psychedelics. Acquired.
  • Bexson Biomedical, novel ketamine formulations for pain and mental health.
  • Bloom Science, microbiome therapeutics platform for neurological disease.
  • Bright Minds, next-generation psychedelics for brain and mental health. IPO.
  • Delix Therapeutics, non-hallucinogenic versions of psychedelic compounds.
  • Freedom Biosciences, next generation psychedelic therapeutics.
  • Gilgamesh Pharmaceuticals, clinical-stage neuroscience biotech. Acquired.
  • Humans Anonymous, anonymous audio spaces for mental health.
  • Imyoo, patient-centric immune biodiscovery platform.
  • Iris Medicine, small-binding RNA medicine for neurodegenerative diseases.
  • Jimini Health, AI-assisted therapy tool for therapists.
  • Journey Clinical, empowering mental health professionals to offer psychedelic therapy.
  • Maya Health, data intelligence platform for psychedelic therapy.
  • Mindstate Design Labs, next-generation psychedelic-inspired medicines.
  • Motif Neurotech, minimally invasive bioelectronic solutions for the brain.
  • Neurode, non-invasive neurostimulation starting with ADHD.
  • Remepy, hybrid treatments combining traditional drugs with digital therapeutics.
  • Sanmai, transcranial focused ultrasound for mental health.
  • Sculpta Bio, programmable RNA splicing medicine for complex brain diseases.
  • Siggy, AI psychiatrist.
  • Tactogen, drug development platform for gentler and safer entactogens.
  • Terran, drug discovery platform for CNS and mental health.
  • Tripp, VR/AR platform for meditation and psychedelic-like experiences.
  • And in stealth: biohybrid BCIs, wearable neurotech, brain data for AI, polypharmacology, organelle models, neuroinflammation biologics, patient data for AI models, a neuron-protective modality, cancer behavioral health, and a mental health marketplace.

Who we are:

  • Matias Serebrinsky, General Partner & Co-Founder. Previously led NVIDIA's accelerator for AI startups, Inception North America, and co-founded CookUnity ($1B ARR). LinkedIn, X.
  • Greg Kubin, General Partner & Co-Founder. Previously co-founded HelloSponsor, a SaaS platform (AngelPad '15). Ex-Morgan Stanley, Viacom. LinkedIn, X.
  • Danny Carbonero PhD, Associate. Ex-Breakout Ventures. PhD in Computational Neuroscience and Biomedical Engineering, Boston University. LinkedIn.
  • Dina Burkitbayeva MBA/MS, Co-Founder. CEO, Freedom Biosciences.
  • Martina Galdos, Operations Lead.
  • Tim Gardner PhD, Venture Partner. Chair of Bioengineering, University of Oregon. Founding member of Neuralink.
  • Negin Mokhtari PhD, Venture Partner. Luma Group, ex-Bioluminescence and Genoa Ventures.

Advisors:

  • John Krystal MD, Chief of Psychiatry, Yale-New Haven.
  • Graham Pechenik JD, patent attorney.
  • Jacob Robinson PhD, CEO, Motif Neurotech. Professor, Electrical and Computer Engineering, Rice University.
  • Chrystal Mavros PhD, microbiology, Columbia University.
  • Alex Amen PhD, BridgeBio, Doudna lab.

Building at the frontier of neuro or looking to get involved as an investor? Write to hi@psymed.ventures.

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